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Icodextrin Intraperitoneal
  • Treatments
  • Dehydration

Icodextrin (Intraperitoneal)

Medically reviewed by Drugs.com. Last updated on Mar 9, 2022.

Intraperitoneal route(Solution)

False elevation of glucose levels has occurred, including up to 2 weeks following discontinuation of therapy, because icodextrin peritoneal dialysis solution interferes with glucose dehydrogenase pyrroloquinolinequinone (GDH-PQQ), glucose-dye-oxidoreductase (GDO), and some glucose dehydrogenase flavin-adenine dinucleotide (GDH-FAD)-based glucose measurements due to the presence of maltose. Use only glucose-specific monitors and test strips in patients using icodextrin peritoneal dialysis solution .

Commonly used brand name(s)

In the U.S.

  • Extraneal

Available Dosage Forms:

  • Solution

Therapeutic Class: Dialysis Solution

Uses for icodextrin

Icodextrin is used for a single daily exchange for the long (8 to 16 hour) dwell during continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD). Icodextrin is a peritoneal dialysis solution. It is used as part of a process of cleaning fluid and waste out of your body when your kidneys do not work correctly.

Icodextrin is available only with your doctor's prescription.

Before using icodextrin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For icodextrin, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to icodextrin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of icodextrin in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of icodextrin the elderly.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking icodextrin, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using icodextrin with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Baloxavir Marboxil
  • Bictegravir
  • Digoxin
  • Eltrombopag
  • Erdafitinib
  • Raltegravir

Using icodextrin with any of ..