Idarucizumab
Generic name: idarucizumab [ EYE-da-roo-KIZ-ue-mab ]
Brand name: Praxbind
Dosage form: intravenous solution (2.5 g/50 mL)
Drug class:Anticoagulant reversal agents
What is idarucizumab?
Idarucizumab is a drug that reverses the effects of another medicine called dabigatran (Pradaxa). Dabigatran is used to prevent blood clots and strokes in people with certain heart disorders. Because the medicine keeps the blood from clotting, people taking dabigatran can bleed more easily.
Idarucizumab is used during a medical emergency to treat severe or uncontrolled bleeding that has been caused by taking dabigatran.
Idarucizumab is also used when an emergency surgery or other invasive medical procedure is needed in a person who takes dabigatran.
Idarucizumab may also be used for purposes not listed in this medication guide.
Warnings
In an emergency, you may not be able to tell caregivers about your health conditions. Make sure any doctor caring for you afterward knows you received idarucizumab.
Before taking this medicine
If possible before you receive idarucizumab, tell your doctor if you have hereditary fructose intolerance. Idarucizumab contains sorbitol (a sugar alcohol). Sorbitol can cause serious or life-threatening metabolic problems in people with hereditary fructose intolerance.
In an emergency, you may not be able to tell caregivers if you are pregnant or breast feeding. Make sure any doctor caring for your pregnancy or your baby knows you received this medicine.
How is idarucizumab given?
Idarucizumab is given as an infusion into a vein. A healthcare provider will give you this injection.
After you receive idarucizumab, you may need follow-up blood tests to help your doctor determine how quickly your blood is clotting.
Once your condition is stable, you may need to restart dabigatran to prevent blood clots. Carefully follow your doctor's instructions about how soon to start taking your medicine(s) again.
What happens if I miss a dose?
Because you will receive idarucizumab in a clinical setting, you are not likely to miss a dose.
What happens if I overdose?
Since idarucizumab is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
What should I avoid after receiving idarucizumab?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Idarucizumab side effects
Get emergency medical help if you have signs of an a...
