Idarucizumab (Intravenous)
Medically reviewed by Drugs.com. Last updated on Jan 31, 2022.
Commonly used brand name(s)
In the U.S.
- Praxbind
Available Dosage Forms:
- Solution
Pharmacologic Class: Monoclonal Antibody Fragment
Uses for idarucizumab
Idarucizumab injection is used in patients who are taking dabigatran (a blood thinner) during emergency or life-threatening situations when bleeding cannot be controlled.
Idarucizumab is to be given only by or under the direct supervision of your doctor.
Before using idarucizumab
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For idarucizumab, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to idarucizumab or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of idarucizumab injection in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of idarucizumab injection in the elderly.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of idarucizumab. Make sure you tell your doctor if you have any other medical problems, especially:
- Bleeding problems or
- Blood clots, history of—Use with caution. May make these conditions worse.
- Hereditary fructose intolerance—Idarucizumab contains sorbitol, which may increase risk for more serious side effects.
Proper use of idarucizumab
A nurse or other trained health professional will give you idarucizumab in a hospital. Idarucizumab is given through a needle placed in one of your veins.