Idecabtagene vicleucel
Generic name: idecabtagene vicleucel [ EYE-de-KAB-ta-jeen-vik-LOO-sel ]
Brand name: Abecma
Dosage form: intravenous suspension (-)
Drug class:Miscellaneous antineoplastics
What is idecabtagene vicleucel?
Idecabtagene vicleucel is an immunotherapy medicine used to treat multiple myeloma in adults. idecabtagene vicleucel is given after at least four other treatments have failed.
Idecabtagene vicleucel is made using white blood cells removed from blood.
Idecabtagene vicleucel is available under a special program. You must be registered in the program and understand the risks and benefits of this medicine.
Idecabtagene vicleucel may also be used for purposes not listed in this medication guide.
Warnings
A serious side effect of this medicine is called cytokine release syndrome, which causes fever, chills, trouble breathing, vomiting, and other symptoms. Your caregivers will have medication available to quickly treat this condition if it occurs.
Idecabtagene vicleucel can also cause life-threatening nerve problems. Tell your caregivers or seek emergency medical attention if you have problems with speech, problems with thinking or memory, confusion, or a seizure.
Before taking this medicine
Tell your doctor if you have ever had:
an active infection or inflammation;
hepatitis B;
cytomegalovirus; or
if you have received a vaccine in the past 6 weeks.
Women may need pregnancy testing before receiving idecabtagene vicleucel. You may also need to use birth control to prevent pregnancy during and shortly after treatment with idecabtagene vicleucel and chemotherapy.
If you receive idecabtagene vicleucel during pregnancy, your baby's blood may need to be tested after it is born. This is to evaluate any effects the medicine may have had on the baby.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
How should I use idecabtagene vicleucel?
Idecabtagene vicleucel is available only at an authorized hospital or clinic, and must be given by specially trained healthcare professionals.
Idecabtagene vicleucel is given after a procedure called leukapheresis (LOO-kuh-fuh-REE-sis).
During leukapheresis, some of your blood is collected through a small tube (catheter) placed into a vein. The catheter is connected to a machine that separates your white blood cells from other parts of the blood. The cells are then sent to a laboratory where they are made into idecabtagene vicleuce...
