Generic name:enasidenib [ EN-a-SID-a-nib ]
Drug class:Miscellaneous antineoplastics
What is Idhifa?
Idhifa targets a specific gene mutation called IDH2, which can affect your bone marrow. IDH2 mutation prevents young blood cells from developing into healthy adult blood cells, which can result in symptoms of acute myeloid leukemia.
Idhifa is used to treat acute myeloid leukemia in adults with an IDH2 mutation.
Idhifa is used when AML has come back or has not improved with prior treatment.
Warnings
Idhifa can cause a condition called differentiation syndrome, which affects blood cells and can be fatal if not treated. This condition may occur within 10 days to 5 months after you start taking this medicine.
Seek medical help right away if you have symptoms of differentiation syndrome: fever, cough, trouble breathing, bone pain, rapid weight gain, or swelling in your arms, legs, underarms, groin, or neck.
Before taking this medicine
You should not use Idhifa if you are allergic to enasidenib.
Before using Idhifa tell your doctor about all your medical conditions or allergies.
You may need to have a negative pregnancy test before starting this treatment. In animal studies, enasidenib caused miscarriage, low birth weight, stillbirth, and birth defects.
Enasidenib may harm an unborn baby. Use a barrier form of birth control (condom or diaphragm with spermicide) to prevent pregnancy while you are using Idhifa. Hormonal contraception (birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy during your treatment.
You should use birth control to prevent pregnancy while using this medicine whether you are a man or a woman. Idh...
