Imipenem and cilastatin

Generic name: imipenem and cilastatin [ IM-i-PEN-em-and-SYE-la-STAT-in ]
Brand names: Primaxin IV, Primaxin IM, Primaxin IV ADD-Vantage
Dosage form: injectable powder for injection (250 mg-250 mg; 500 mg-500 mg)
Drug class:Carbapenems

Medically reviewed by Drugs.com on Dec 17, 2021. Written by Cerner Multum.

What is imipenem and cilastatin?

Imipenem and cilastatin is a combination medicine used to treat severe infections of the heart, lungs, bladder, kidneys, skin, blood, bones, joints, stomach, or female reproductive organs.

Imipenem and cilastatin may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use imipenem and cilastatin if you are allergic to imipenem or cilastatin.

Tell your doctor if you have ever had:

• any allergies;

• seizures or epilepsy;

• meningitis;

• a head injury or brain tumor;

• kidney disease (or if you are on dialysis); or

• an allergy to any type of antibiotic.

Tell your doctor if you are pregnant or breast-feeding.

How should I use imipenem and cilastatin?

Follow all directions on your p...