Immune globulin and hyaluronidase (Subcutaneous)
Medically reviewed by Drugs.com. Last updated on May 30, 2022.
Thrombosis may occur with immune globulin/recombinant human hyaluronidase in patients with or without known risk factors. Risk factors may include advanced age, prolonged immobilization, hypercoagulable conditions, history of venous or arterial thrombosis, use of estrogens, indwelling central vascular catheters, hyperviscosity, and cardiovascular risk factors. Adequate hydration prior to administration is recommended. Administer at the minimum dose and infusion rate practicable in patients at risk of thrombosis. Monitor for signs and symptoms of thrombosis and assess blood viscosity in patients at risk of hyperviscosity .
Commonly used brand name(s)
In the U.S.
- HyQvia
Available Dosage Forms:
- Solution
Uses for immune globulin and hyaluronidase
Immune globulin and recombinant human hyaluronidase injection is used to treat primary immunodeficiency (PI) in adults.
Immune globulin injection belongs to a group of medicines known as immunizing agents. It is used to prevent or treat diseases that occur when your body has a weak immune system. Immune globulin contains antibodies that make your immune system stronger. Hyaluronidase injection is a spreading substance that helps improve the uptake of immune globulin into the body.
Immune globulin and hyaluronidase is available only with your doctor's prescription.
Before using immune globulin and hyaluronidase
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For immune globulin and hyaluronidase, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to immune globulin and hyaluronidase or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of immune globulin and recombinant human hyaluronidase injection in the pediatric population. Safety has not been established.
Geriatric
Although appropriate studies on the relationship of age to the effects of immune globulin and recombinant human hyaluronidase injection have not been performed in the geriatric population, geriatric-specific problems are not expected to limit the usefulness of immune globulin and recombinant human hyaluronidase injection in the elderly. However, elderly patients are more likely to have age-related blood clotting problems, kidney or heart problems, which may require caution for patients receiving immune globulin and recombinant human hyaluronidase injection.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an inte..
