Inotersen
Generic name: inotersen [ IN-oh-TER-sen ]
Brand name: Tegsedi
Dosage form: subcutaneous solution (284 mg/1.5 mL)
Drug class:Miscellaneous metabolic agents
What is inotersen?
Inotersen is used to treat polyneuropathy (damage of multiple nerves throughout the body) in adults with hATTR. inotersen can help reduce symptoms such as pain, numbness, tingling, abnormal heartbeats, diarrhea, constipation, weakness, and problems with movement in your arms or legs.
Inotersen is available only from a certified pharmacy under a special program.
Inotersen may also be used for purposes not listed in this medication guide.
Warnings
Inotersen can make it easier for you to bleed, even from a minor injury. Seek medical attention if you have bleeding that will not stop.
Bleeding may also happen inside your body. Call your doctor at once if you have signs such as severe headache, neck stiffness, bleeding in the whites of your eyes, black or bloody stools, pink or brown urine, or coughing up blood or vomit that looks like coffee grounds.
Before taking this medicine
You should not use inotersen if you are allergic to it, or if you have:
low levels of platelets in your blood (your doctor will test you for this); or
kidney problems caused by using inotersen in the past.
Tell your doctor if you have ever had:
a bleeding or blood clotting disorder; or
kidney disease.
Tell your doctor if you are pregnant or breastfeeding.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of inotersen on the baby.
How should I use inotersen?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Inotersen is injected under the skin once weekly. Your care provider will show you where on your body to inject inotersen. Use a different place each time you give an injection. Do not inject into the same place two times in a row.
Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instructions.
Prepare an injection only when you are ready to give it. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine.
Use this m...
