Inotuzumab ozogamicin
Generic name: inotuzumab ozogamicin [ IN-oh-TOOZ-ue-mab-OH-zoe-ga-MYE-sin ]
Brand name: Besponsa
Dosage form: intravenous powder for injection (0.9 mg)
Drug class:Miscellaneous antineoplastics
What is inotuzumab ozogamicin?
Inotuzumab ozogamicin is a monoclonal antibody linked to a chemotherapy drug. Monoclonal antibodies are made to target and destroy only certain cells in the body. This may help to protect healthy cells from damage.
Inotuzumab ozogamicin is used to treat a certain type of acute lymphocytic leukemia that has come back or has not responded after prior chemotherapy.
Inotuzumab ozogamicin may also be used for purposes not listed in this medication guide.
Warnings
inotuzumab ozogamicin may cause serious or life-threatening liver problems, including veno-occlusive disease (blocked blood vessels in the liver that can lead to liver damage).
Call your doctor at once if you have signs of liver problems, such as upper stomach pain, jaundice (yellowing of the skin or eyes), rapid weight gain, or painful swelling in your midsection.
Before taking this medicine
Tell your doctor if you have ever had:
liver problems;
a stem cell transplant;
long QT syndrome (in you or a family member); or
an electrolyte imbalance (such as low levels of potassium or magnesium in your blood).
You may need to have a negative pregnancy test before starting this treatment.
Inotuzumab ozogamicin can harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine, whether you are a man or a woman. Men should use condoms. Inotuzumab ozogamicin use by either parent may cause birth defects.
If you are a woman, keep using birth control for at least 8 months after your last dose of inotuzumab ozogamicin. If you are a man, keep using condoms for at least 5 months after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using inotuzumab ozogamicin.
This medicine may affect fertility (ability to have children) in both men and women. However, it is important to use birth control to prevent pregnancy because inotuzumab ozogamicin may harm the baby if a pregnancy does occur.
You should not breastfeed while using this medicine and for at least 2 months after your last dose.
How is inotuzumab ozogamicin given?
Inotuzumab ozogamicin is given as an infusion into a vein. A healthcare pro...
