Inotuzumab ozogamicin (Intravenous)

Medically reviewed by Drugs.com. Last updated on Apr 27, 2022.

Commonly used brand name(s)

In the U.S.

• Besponsa

Available Dosage Forms:

• Powder for Solution

Therapeutic Class: Antineoplastic Agent

Pharmacologic Class: Antibody Drug Conjugate

Uses for inotuzumab ozogamicin

Inotuzumab ozogamicin injection is used to treat acute lymphoblastic leukemia (ALL) that has come back or after other medicines did not work well. Leukemia is a type of cancer where the body makes abnormal white blood cells.

Inotuzumab ozogamicin is an antineoplastic (cancer) medicine. It interferes with the growth of cancer cells, which are eventually destroyed by the body. Since the growth of normal cells may also be affected by inotuzumab ozogamicin, other side effects can occur. Before you begin treatment, talk to your doctor about the benefits of inotuzumab ozogamicin as well as the possible risks of using it.

Inotuzumab ozogamicin is to be given only by or under the direct supervision of your doctor.

Before using inotuzumab ozogamicin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For inotuzumab ozogamicin, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to inotuzumab ozogamicin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of inotuzumab ozogamicin injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of inotuzumab ozogamicin injection in the elderly.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving inotuzumab ozogamicin, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using inotuzumab ozogamicin with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.