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Insulin degludec and liraglutide
  • Treatments
  • Diabetes
  • Type 2

Insulin degludec and liraglutide

Generic name: insulin degludec and liraglutide [ IN-su-lin-de-GLOO-dek-and-LIR-a-GLOO-tide ]
Brand name: Xultophy
Dosage form: subcutaneous solution (100 units-3.6 mg/mL)
Drug class:Antidiabetic combinations

Medically reviewed by Drugs.com on Mar 28, 2022. Written by Cerner Multum.

What is insulin degludec and liraglutide?

Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin degludec is a long-acting insulin that starts to work several hours after injection and keeps working evenly for 24 hours.

Liraglutide is similar to a hormone that occurs naturally in the body and helps control blood sugar, insulin levels, and digestion.

Insulin degludec and liraglutide is a combination medicine used to lower blood sugar in adults with type 2 diabetes mellitus. insulin degludec and liraglutide should be used together with diet and exercise.

Insulin degludec and liraglutide is usually given when your blood sugar levels have not been well controlled by using other medications.

Insulin degludec and liraglutide is not for people with type 1 diabetes.

Insulin degludec and liraglutide may also be used for purposes not listed in this medication guide.

Warnings

You should not use this medicine if you have multiple endocrine neoplasia type 2 (tumors in your glands), a personal or family history of medullary thyroid cancer, insulin-dependent diabetes, or if you are having an episode of low blood sugar or diabetic ketoacidosis.

In animal studies, liraglutide caused thyroid tumors or thyroid cancer. It is not known whether these effects would occur in people.

Call your doctor at once if you have signs of a thyroid tumor, such as swelling or a lump in your neck, trouble swallowing, a hoarse voice, or shortness of breath.

Before taking this medicine

You should not use insulin degludec and liraglutide if you are allergic to insulin or liraglutide. Do not use this medicine during an episode of low blood sugar, or if you have:

  • multiple endocrine neoplasia type 2 (tumors in your glands);

  • a personal or famil...