Insulin degludec and liraglutide (Subcutaneous)
Medically reviewed by Drugs.com. Last updated on Mar 14, 2022.
Liraglutide, a component of insulin degludec/liraglutide is known to cause dose-dependent and treatment-duration dependent thyroid C-cell tumors in rats and mice. It is unknown whether this component causes thyroid C-cell tumors in humans. Use is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) and in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) .
Available Dosage Forms:
- Solution
Therapeutic Class: Antidiabetic
Pharmacologic Class: Insulin, Long Acting
Uses for insulin degludec and liraglutide
Insulin degludec and liraglutide combination injection is used to treat a type of diabetes mellitus (sugar diabetes) called type 2 diabetes.
Insulin degludec is a long-acting type of insulin that works slowly, over about 24 hours. Insulin is one of many hormones that help the body turn the food we eat into energy. This is done by using the glucose (sugar) in the blood as quick energy. Also, insulin helps us store energy that we can use later. When you have diabetes mellitus, your body cannot make enough insulin or does not use insulin properly. This causes you to have too much sugar in your blood. Like other types of insulin, insulin degludec is used to keep your blood sugar level close to normal. Liraglutide is to be used when diet and exercise do not result in good blood sugar control.
Insulin degludec and liraglutide is available only with your doctor's prescription.
Before using insulin degludec and liraglutide
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For insulin degludec and liraglutide, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to insulin degludec and liraglutide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of insulin degludec and liraglutide combination injection in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of insulin degludec and liraglutide combination injection in the elderly. However, elderly patients are more likely to have age-related hypoglycemia, which may require caution and an adjustment in the dose for patients receiving insulin degludec and liraglutide.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, y..
