Insulin glargine and lixisenatide (Subcutaneous)

Medically reviewed by Drugs.com. Last updated on Mar 29, 2022.

Commonly used brand name(s)

In the U.S.

• Soliqua 100/33

Available Dosage Forms:

• Solution

Therapeutic Class: Antidiabetic

Pharmacologic Class: Insulin, Long Acting

Uses for insulin glargine and lixisenatide

Insulin glargine and lixisenatide combination is used to treat a type of diabetes mellitus (sugar diabetes) called type 2 diabetes.

Insulin glargine is a long-acting type of insulin that works slowly, over about 24 hours. Insulin is one of many hormones that help the body turn the food we eat into energy. This is done by using the glucose (sugar) in the blood as quick energy. Also, insulin helps us store energy that we can use later. When you have diabetes mellitus, your body cannot make enough insulin or does not use insulin properly. This causes you to have too much sugar in your blood. Like other types of insulin, insulin glargine is used to keep your blood sugar level close to normal. Lixisenatide is to be used when diet and exercise do not result in good blood sugar control.

Insulin glargine and lixisenatide is available only with your doctor's prescription.

Before using insulin glargine and lixisenatide

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For insulin glargine and lixisenatide, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to insulin glargine and lixisenatide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of Soliqua® in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Soliqua® in the elderly. However, elderly patients are more likely to have age-related hypoglycemia, which may require caution and an adjustment in the dose for patients receiving Soliqua®.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking insulin glargine and lixisenatide, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using insulin glargine and lixisenatide with any of the following medicines is usually not recommended, but may be required in s...