Invega Trinza
Generic name:paliperidone palminate
Dosage form: extended-release suspension for intramuscular injection
Drug class:Atypical antipsychotics
What is Invega Trinza?
Invega Trinza is an atypical antipsychotic that is given once every 3 months. It is used to treat a mental disorder called schizophrenia.
Invega Trinza contains paliperidone. Another well-known antipsychotic drug called Risperdal (risperidone) is converted into paliperidone once it is in the body. Invega Trinza is an extended-release version of paliperidone that helps to overcome the fluctuations in blood levels of the drug that are seen after it is taken by mouth as an immediate-release formulation such as Risperdal. It also helps to avoid the problem of remembering to take a medication everyday.
It is not fully understood how Invega Trinza works, but it helps to adjust the levels of chemicals in the brain called dopamine and serotonin. These chemicals are called neurotransmitters and it's thought that an imbalance in these chemicals plays a role in schizophrenia.
Invega Trinza was approved by the US Food and Drug Administration (FDA) in 2015.
What is Invega Trinza used for?
Invega Trinza is a prescription medicine given by injection by a healthcare professional and used to treat schizophrenia.
Invega Trinza is used in people who have been treated with Invega Sustenna 1 time a month injections for at least 4 months.
It is not known if Invega Trinza is safe and effective in children under 18 years of age.
Important Information
Invega Trinza can cause serious side effects, including:
- Increased risk of death in elderly people who are confused, have memory loss and have lost touch with reality (dementia-related psychosis). Invega Trinza is not for treating dementia-related psychosis.
Who should not receive Invega Trinza?
Do not receive Invega Trinza if you:
- are allergic to paliperidone palmitate, risperidone, or any of the ingredients in Invega Trinza. See below for a complete list of ingredients in Invega Trinza.
What should I tell my doctor before receiving Invega Trinza?
Before you receive Invega Trinza, tell your healthcare provider about all your medical conditions, including if you:
- have had Neuroleptic Malignant Syndrome (NMS)
- have or have had heart problems, including a heart attack, heart failure, abnormal heart rhythm, or long QT syndrome
- have or have had low levels of potassium or magnesium in your blood
- have or have had uncontrolled movements of your tongue, face, mouth, or jaw (tardive dyskinesia)
- have or have had kidney or liver problems
- have diabetes or have a family history of diabetes
- have had a low white blood cell count
- have had problems with dizziness or fainting or are being treated for high blood pressure
- have or have...
