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Iobenguane I-131
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Iobenguane I-131

Generic name: iobenguane I-131 [ EYE-oh-BEN-gwane ]
Brand name: Azedra
Dosage form: intravenous solution (-)
Drug class:Therapeutic radiopharmaceuticals

Medically reviewed by Drugs.com on Nov 10, 2021. Written by Cerner Multum.

What is iobenguane I-131?

Iobenguane I-131 is a radiopharmaceutical (RAY dee oh far ma SOO tik al) medicine that is used to treat a certain type of adrenal gland tumor (pheochromocytoma).

Iobenguane I-131 is also used to treat a rare type of nerve cell tumor (paraganglioma) that can spread throughout the body.

Iobenguane I-131 is for use in adults and children who are at least 12 years old.

Iobenguane I-131 may also be used for purposes not listed in this medication guide.

Warnings

Both men and women using iobenguane I-131 should use effective birth control to prevent pregnancy. Iobenguane I-131 can harm an unborn baby if the mother or father is receiving this medicine.

If you are a woman, keep using birth control for at least 7 months after your last dose. If you are a man, keep using birth control for at least 4 months after your last dose.

Before taking this medicine

Tell your doctor if you have ever had:

  • kidney disease; or

  • if you have routine "INR" or prothrombin time tests.

Using iobenguane I-131 may increase your risk of developing other cancers, such as leukemia. Ask your doctor about this risk.

You may need to have a negative pregnancy test before starting this treatment.

Iobenguane I-131 can harm an unborn baby if the mother or the father is receiving this medicine.

  • If you are a woman, do not use iobenguane I-131 if you are pregnant. Use effective birth control to prevent pregnancy while you are receiving this medicine and for at least 7 months after your last dose.

  • If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 4 months after your last dose.

  • Tell your doctor right away if a pregnancy occurs while either the mother or the father is receiving iobenguane I-131.

This medicine may affect fertility (ability to have children) in both men and women. However, it is important to use birth control to prevent pregnancy because iobenguane I-131 can harm an unborn baby.

Do not breast-feed while using this medicine, and for at least 80 days after your last dose.

How should I take iobenguane I-131?

Iobenguane I-131 is given as an infusion into a vein. A healthcare provider will give you this injection.

Iobenguane I-131 is usuall...