Generic name: Ipratropium bromide
Dosage form: inhalation solution
Drug class:Anticholinergic bronchodilators
Medically reviewed by Drugs.com. Last updated on Apr 1, 2022.
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Ipratropium Description
The active ingredient in Ipratropium Bromide Inhalation Solution, USP is Ipratropium bromide monohydrate, USP. It is an anticholinergic bronchodilator chemically described as 8-azoniabicyclo[3.2.1]-octane,3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1- methylethyl)-, bromide, monohydrate (endo, syn)-,(±)-; a synthetic quaternary ammonium compound, chemically related to atropine.
Ipratropium bromide is a white crystalline substance, freely soluble in water and lower alcohols. It is a quaternary ammonium compound and thus exists in an ionized state in aqueous solutions. It is relatively insoluble in non-polar media.
Ipratropium Bromide Inhalation Solution, USP is administered by oral inhalation with the aid of a nebulizer. Each mL contains Ipratropium bromide, USP 0.02% (anhydrous basis) in a sterile, preservative-free, isotonic saline solution, pH adjusted to 3.4 (3 to 4) with hydrochloric acid.
Ipratropium - Clinical Pharmacology
