Isopto Carpine Ophthalmic Solution

Generic name:pilocarpine hydrochloride
Dosage form: ophthalmic solution
Drug class:Ophthalmic glaucoma agents

Medically reviewed by Drugs.com. Last updated on Oct 1, 2021.

Indications and Usage for Isopto Carpine Ophthalmic Solution

Isopto® Carpine is indicated for the:

Reduction of Elevated Intraocular Pressure (IOP) in Patients With Open-Angle Glaucoma or Ocular Hypertension

Management of Acute Angle-Closure Glaucoma

Prevention of Postoperative Elevated IOP Associated With Laser Surgery

Induction of Miosis

Isopto Carpine Ophthalmic Solution Dosage and Administration

Reduction of Elevated IOP in Patients With Open-Angle Glaucoma or Ocular Hypertension

One drop of Isopto® Carpine 1%, 2%, or 4% should be applied topically in the eye(s) up to four times daily. Pilocarpine-naïve patients should be started on the 1% concentration as higher concentrations are often not tolerated initially. The frequency of instillation and concentration of Isopto® Carpine are determined by the severity of the elevated intraocular pressure and miotic response of the patient.

To limit systemic exposure to pilocarpine, patients may be instructed to perform punctal occlusion for 2 minutes after instillation of Isopto® Carpine ophthalmic solution.

Management of Acute Angle-Closure Glaucoma

Prior to Isopto® Carpine use, treatment with secretory suppressants and hyperosmotic agents may be needed to lower IOP below 50 mmHg and relieve iris ischemia. For initial management of acute angle-closure glaucoma, one drop of Isopto® Carpine 1% or 2% may be applied topically in the eye(s) up to three times over a 30-minute period.

If lase...