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Isosorbide dinitrate Oral, Sublingual
  • Treatments
  • Angina Pectoris Prophylaxis
  • Isosorbide dinitrate

Isosorbide dinitrate

Medically reviewed by Drugs.com. Last updated on Mar 13, 2022.

Commonly used brand name(s)

In the U.S.

  • Dilatrate-SR
  • Isochron
  • IsoDitrate
  • Isordil Titradose

In Canada

  • Apo-Isdn
  • Isordil

Available Dosage Forms:

  • Tablet
  • Capsule, Extended Release
  • Tablet, Extended Release

Therapeutic Class: Antianginal

Chemical Class: Nitrate

Uses for isosorbide dinitrate

Isosorbide dinitrate is used to prevent angina (chest pain) caused by coronary artery disease. It does not work fast enough to relieve the pain of an angina attack that has already started.

Isosorbide dinitrate belongs to the group of medicines called nitrates. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its work load. When used regularly on a long-term basis, this helps prevent angina attacks from occurring.

Isosorbide dinitrate is available only with your doctor's prescription.

Before using isosorbide dinitrate

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For isosorbide dinitrate, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to isosorbide dinitrate or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of isosorbide dinitrate in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of isosorbide dinitrate in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving isosorbide dinitrate.

Breastfeeding

There are ...