Istradefylline
Generic name: istradefylline [ IS-tra-DEF-i-lin ]
Brand name: Nourianz
Dosage form: oral tablet (20 mg; 40 mg)
Drug class:Miscellaneous antiparkinson agents
What is istradefylline?
Istradefylline is given with levodopa and carbidopa to treat "wearing-off" episodes (muscle stiffness, loss of muscle control) in people with Parkinson's disease.
Istradefylline may also be used for purposes not listed in this medication guide.
Warnings
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
Tell your doctor if you have ever had:
abnormal muscle movements;
mental illness or psychosis;
liver disease; or
if you smoke.
Tell your doctor if you are pregnant or breastfeeding.
How should I take istradefylline?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Istradefylline is usually taken once per day. Follow your doctor's dosing instructions very carefully.
You may take istradefylline with or without food.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking istradefylline?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Istradefylline side effects
Get emergency medical help if you have signs of an allergic reaction:hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Istradefylline may cause serious side effects. Call your doctor at once if you have:
uncontrolled or involuntary muscle movements;
unusual thoughts or behavior;
confusion, hallucinations; or
risk-taking behavior, being impulsive.
You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking istradefylline. Talk wit...