Ivermax
Generic name: ivermectin pour-on
Dosage form: FOR ANIMAL USE ONLY
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5 mg ivermectin/mL
PARASITICIDE
Kills: Roundworms (including Brown Stomach Worm), Lungworms, Grubs, Sucking Lice, Biting Lice, Mange Mite, Horn Flies
WARNING! FLAMMABLE! KEEP AWAY FROM HEAT, SPARKS, OPEN FLAME AND OTHER SOURCES OF IGNITION.
Restricted Drug (California) – Use Only as Directed.
FOR ANIMAL USE ONLY
Keep Out of Reach of Children
Approved by FDA under ANADA # 200-340
See attached booklet for complete indications and use directions.
Parasiticide
Consult your veterinarian for assistance in the diagnosis, treatment and control of parasitism.
Introduction
Ivermax® Pour-On for Cattle (ivermectin topical solution) delivers internal and external parasite control in one convenient low-volume application. Ivermax® Pour-On for Cattle contains ivermectin, a unique chemical entity.
Mode of Action
Ivermectin is a member of the macrocylic lactone class of endectocides which have a unique mode of action. Compounds of the class bind selectively and with high affinity to glutamate-gated chloride ion channels which occur in invertebrate nerve and muscle cells.
This leads to an increase in the permeability of the cell membrane to chloride ions with hyperpolarization of the nerve or muscle cell, resulting in paralysis and death of the parasite. Compounds of this class may also interact with other ligand-gated chloride channels, such as those gated by the neurotransmitter gamma-aminobutyric acid (GABA).
The margin of safety for compounds of this class is attributable to the fact that mammals do not have glutamate-gated chloride channels, the macrocyclic lactones have a low affinity for other mammalian ligand-gated chloride channels and they do not readily cross the blood-brain barrier.
Indications
Ivermax® Pour-On for Cattle applied at the recommended dose level of 500 mcg/kg is indicated for the effective treatment and control of these parasites.
Gastrointestinal Roundworms
Ostertagia ostertagi (including inhibited stage) (adults and L4)
Haemonchus placei (adults and L4)
Trichostrongylus axei (adults and L4)
T. colubriformis (adults and L4)
Cooperia oncophora (adults and L4)
Cooperia punctate ...
