Class: Anthelmintics
VA Class: AP200
Chemical Name: A mixture of Ivermectin Component B1a (2aE,4E,8E)-(5′S,6S,6′R,7S,11R,13R,15S,17aR,20R,20aR,20bS)-6′-(S)-sec-butyl-3′,4′,5′,6,6′,7,10,11,14,15,17a,20,20a,20b-tetradecahydro-20,20b-dihydroxy-5′,6,8,19-tetramethyl-17-oxospiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]-benzodioxacyclooctadecin-13,2′-[2H]pyran]-7-yl-2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-l-arabino-hexopyranosyl)-3-O-methyl-α-l-arabino-hexopyranoside) and Ivermectin Component B1b (2aE,4E,8E)-(5′S,6S,6′R,7S,11R,13R,15S,17aR,20R,20aR,20bS)-3′,4′,5′,6,6′,7,10,11,14,15,17a,20,20a,20b-tetradecahydro-20,20b-dihydroxy-6′-isopropyl-5′,6,8,19-tetramethyl-17-oxospiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]-benzodioxacyclooctadecin-13,2′-[2H]pyran]-7-yl-2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-l-arabino-hexopyranosyl)-3-O-methyl-α-l-arabino-hexopyranoside)
Molecular Formula: A mixture of Ivermectin Component B1a (C48H74O14) and Ivermectin Component B1b (C47H72O14)
CAS Number: 70288-86-7
Brands: Stromectol
Warning
Special Alerts:
[Posted 04/10/2020]
AUDIENCE: Consumer, Health Professional, Pharmacy, Veterinary
ISSUE: FDA is concerned about the health of consumers who may self-medicate by taking ivermectin products intended for animals, thinking they can be a substitute for ivermectin intended for humans.
BACKGROUND: The FDA's Center for Veterinary Medicine has recently become aware of increased public visibility of the antiparasitic drug ivermectin after the announcement of a research article that described the effect of ivermectin on SARS-CoV-2 in a laboratory setting. The Antiviral Research pre-publication paper, “The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro” documents how SARS-CoV-2 (the virus that causes COVID-19) responded to ivermectin when exposed in a petri...
