Ixazomib
Generic name: ixazomib [ ix-AZ-oh-mib ]
Brand name: Ninlaro
Dosage form: oral capsule (2.3 mg; 3 mg; 4 mg)
Drug class:Proteasome inhibitors
What is ixazomib?
Ixazomib is used to treat multiple myeloma (bone marrow cancer), in combination chemotherapy with lenalidomide and dexamethasone.
This combination is usually given after treatment with at least one other cancer medicine has failed.
Ixazomib may also be used for purposes not listed in this medication guide.
Warnings
Do not use ixazomib with lenalidomide if you are pregnant, or if you are a man and your sexual partner is pregnant. Lenalidomide is known to cause severe, life-threatening birth defects or death of a baby if the mother or the father is taking ixazomib at the time of conception or during pregnancy.
Before taking this medicine
You should not use ixazomib if you are allergic to it.
Tell your doctor if you have ever had:
liver disease; or
kidney disease (or if you are on dialysis).
Ixazomib may harm an unborn baby. Both men and women should use effective birth control to prevent pregnancy while taking ixazomib, and for at least 90 days after the last dose.
If you are a woman also taking dexamethasone: If you use birth control pills or other hormonal contraception (injections, implants, skin patches, vaginal rings), also use a barrier form of birth control such as a condom, diaphragm, cervical cap, or contraceptive sponge.
Ixazomib is used together with lenalidomide. Do not use ixazomib with lenalidomide if you are pregnant, or if you are a man and your sex partner is pregnant. Lenalidomide is known to cause severe, life-threatening birth defects or death of a baby if the mother or the father is taking this medicine at the time of conception or during pregnancy.
Carefully follow all instructions about the use of of birth control while using ixazomib with lenalidomide, whether you are a man or a woman. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using these medicines.
Do not breastfeed while using ixazomib, and for at least 90 days after your last dose.
How should I take ixazomib?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
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