Generic name:ruxolitinib [ RUX-oh-LI-ti-nib ]
Drug class:Multikinase inhibitors
What is Jakafi?
Jakafi works by blocking certain enzymes in the body that affect blood cell production.
Jakafi is used to treat certain types of myelofibrosis in adults.
Jakafi is used to treat polycythemia vera in adults who have already taken a medicine called hydroxyurea and it did not work well enough or they could not tolerate it.
Jakafi is used to treat acute graft versus host disease (aGVHD) in adults and children 12 years of age and older who have taken corticosteroids and they did not work well enough.
Jakafi is also used to treat chronic graft-versus-host-disease (cGVHD) in adults and children 12 years of age and older who have taken one or two types of treatments and they did not work well enough.
Warnings
You should not use Jakafi if you are allergic to ruxolitinib, or if you have severe kidney disease.
Before you take this medicine, tell your doctor if you have liver or kidney disease, if you are on dialysis, or if you are pregnant.
You should not breast-feed while you are using this medicine.
To be sure Jakafi is helping your condition and not causing harmful effects, your blood will need to be tested often. This will help your doctor determine the best dose for you to use. When you first start taking this medicine, your blood will need to be tested every 2 to 4 weeks. Do not miss any follow-up visits to your doctor.
Grapefruit and grapefruit juice may interact with Jakafi and can affect the amount of the medication in your blood. Discuss the use of grapefruit products with your doctor.
Follow all directions on your medicine label and package. Tell each of your healthcare pr...
