Generic name:metformin and sitagliptin [ met-FOR-min-and-SI-ta-glip-tin ]
Brand names: Janumet, Janumet XR
Drug class:Antidiabetic combinations
What is Janumet?
Janumet contains a combination of metformin and sitagliptin. Metformin and sitagliptin are oral diabetes medicines that help control blood sugar levels.
Metformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines. Sitagliptin works by regulating the levels of insulin your body produces after eating.
Janumet is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.
Janumet is not used to treat type 1 diabetes.
Warnings
You should not use Janumet if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment with insulin).
Janumet may cause a serious condition called lactic acidosis. Get emergency medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or uneven heart rate, dizziness, or feeling very weak or tired.
Janumet may also lead to a serious condition called pancreatitis. Call your doctor right away if you have severe stomach pains with or without vomiting.
Before taking this medicine
You should not use Janumet if you are allergic to metformin or sitagliptin (Januvia), or if you have severe kidney disease.
To make sure Janumet is safe for you, tell your doctor if you have ever had:
kidney disease (your kidney function may need to be checked before a...
