J-COF DHC

Generic name: dihydrocodeine bitartrate, brompheniramine maleate, pseudoephedrine hydrochloride
Dosage form: oral liquid
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com. Last updated on Jan 24, 2022.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

CIII
J-COF DHC
Liquid

Antitussive · Antihistamine
Decongestant
Rx Only

DESCRIPTION
Each teaspoonful (5 mL) for oral administration contains:
Dihydrocodeine Bitartrate.....7.5 mg
(WARNING-May be habit forming)
Brompheniramine Maleate.....3 mg
Pseudoephedrine Hydrochloride.....15 mg

This product contains the following inactive ingredients:
Glycerin, Propylene Glycol, Sorbitol, Citric Acid, Sodium Citrate, Sodium Saccharin, Grape Flavor, Purified Water.

Dihydrocodeine Bitartrate is an antitussive having the chemical name,Morphine-6-ol,4,5-epoxy-3-methoxy-17-methyl-,(5α,6α)-2,3-dihydroxybutanedioate (1:1) (salt). It has the following structural formula:



Brompheniramine Maleate is an antihistamine having the chemical name, 2-Pyridinepropanamine,γ-(4-bromophenyl)-N,N-dimethyl-, (±)-,(Z)-2-butenedioate (1:1). with the following structure:



Pseudoephedrine Hydrochloride is a decongestant having the chemical name, Benzenemethanol, α-[1-(methylamino) ethyl]-, [S-(R*,R*)-, hydrochloride. It has the following structural formula:

J-COF DHC - Clinical Pharmacology

Dihydrocodeine is a semisynthetic narcotic analgesic antitussive related to codeine, with multiple actions qualitatively similar to those of codeine: the most prominent of these involve the central nervous system