Jynneos (Subcutaneous)

Generic name:smallpox monkeypox vaccine, live non-replicating (subcutaneous route) [ SMAWL-pox-MUN-kee-pox-vak-SEEN, lyve-non-- REP-li-kay-ting ]

Medically reviewed by Drugs.com. Last updated on Feb 16, 2022.

Commonly used brand name(s)

In the U.S.

• Jynneos

Uses for Jynneos

Smallpox monkeypox vaccine, live non-replicating, is an active immunizing agent used to prevent smallpox and monkeypox infection in adults who may be at high risk to have this disease. It works by causing your immune system to produce its own protection (antibodies) against the virus.

This vaccine is to be given only by or under the supervision of your doctor or other authorized health care professional.

Before using Jynneos

In deciding to use a vaccine, the risks of taking the vaccine must be weighed against the good it will do. This is a decision you and your doctor will make. For this vaccine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of smallpox monkeypox vaccine, live non-replicating, in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies have not been performed on the relationship of age to the effects of smallpox monkeypox vaccine, live non-replicating in the elderly 65 years of age and older. Safety and efficacy have not been established.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this vaccine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Receiving this vaccine with any of the following medicines is not recommended. Your doctor may decide not to use this vaccine or change some of the other medicines you take.

• Deflazacort

Receiving this vaccine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Anifrolumab-fnia
• Canakinumab
• Dupilumab
• Fingolimod
• Ixekizumab
• Ozanimod
• Ponesimod
• Secukinumab
• Siponimod
• Tralokinumab-ldrm<...