Kalbitor

Generic name:ecallantide [ e-KAL-an-tide ]
Drug class:Hereditary angioedema agents

Medically reviewed by Drugs.com. Last updated on Jul 2, 2021.

What is Kalbitor?

Kalbitor is used to treat attacks of hereditary angioedema (an immune system disorder). This medicine is for use in adults and children at least 12 years old.

Kalbitor is not a cure for hereditary angioedema.

Kalbitor may also be used for other purposes not listed in this medication guide.

Warnings

You should not be treated with Kalbitor if you are allergic to ecallantide. Ecallantide can cause a serious allergic reaction within 1 hour after receiving an injection. Symptoms include wheezing, cough, trouble breathing or swallowing, itching, hives, dizziness, fainting, or swelling in your face or throat Tell your doctor if you have a history of any type of allergy.

In an emergency situation it may not be possible to tell your caregivers about your health conditions. Make sure any doctor caring for you afterward knows you have received this medicine.

Before receiving this medicine

You should not be treated with Kalbitor if you are allergic to ecallantide.

If possible before you receive Kalbitor, tell your doctor if you have a history of any type of allergy.

It is not known whether Kalbitor will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether ecallantide passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

In an emergency situation it may not be possible to tell your caregivers if you are pregnant or breast-feeding. Make sure any doctor caring for your pregnancy or your baby knows you have received this medicine.

How is Kalbitor given?

Kalbitor is injected under the skin. A healthcare provider will give you this injection.

You will be watched closely after receiving your injection, to make sure you do not have an allergic reaction to the medication.

Kalbitor is usually given in 3 separate injections. If you still have symptoms of the angioedema attack, more injections may be given within 24 hours.

Dosing information

Usual Adult Dose for Hereditary Angioedema:

30 mg subcutaneously in three 10 mg injections; may repeat an additional 30 mg within 24 hours if attack persists.

Usual Pediatric Dose for Hereditary Angioedema:

12 years and older: 30 mg subcutaneously in three 10 mg injections; may repeat an additional 30 mg within 24 hours if attack persists.