Kerendia

Generic name:finerenone
Dosage form: tablets
Drug class:Aldosterone receptor antagonists

Medically reviewed by Judith Stewart, BPharm. Last updated on Oct 1, 2021.

What is Kerendia?

Kerendia is a prescription medicine used to treat adults with chronic kidney disease associated with type 2 diabetes to reduce the risk of:

• Worsening of kidney disease
• End-stage kidney disease (ESKD)
• Death due to cardiovascular disease
• Heart attack
• Hospitalization for heart failure

Who should not take Kerendia?

You should not take Kerendia if you:

• Have problems with your adrenal glands
• Take certain medications called CYP3A4 inhibitors. Ask your healthcare provider if you are not sure if you are taking any of these medications.
  • Administration of Kerendia with strong inhibitors of CYP3A4 (such as clarithromycin, itraconazole, ketoconazole, voriconazole, posaconazole, voriconazole, ritonavir, lopinavir, cobicistat) should be avoided.
  • Administration of Kerendia with moderate and weak inhibitors of CYP3A4 (such as amiodarone, erythromycin, fluconazole, diltiazem, verapamil, conivaptan) should only be used under medical supervision so that potassium levels can be monitored and dosages adjusted if needed.

Before you take Kerendia

Before you take Kerendia, tell your healthcare provider about all your medical conditions, including if you:

• Have high potassium levels in your blood (hyperkalemia) or take medications that may increase potassium levels in your blood. Kerendia can cause hyperkalemia. Your healthcare provider will check your potassium levels before and during treatment.
• Have severe liver problems.
• Are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. Avoid breastfeeding during treatment and one day after treatment is stopped.

Tell your healthcare provider about all the prescription and over-the-counter medicines you take,..