Kimidess

Generic name:desogestrel and ethinyl estradiol
Dosage form: tablets
Drug class:Contraceptives

Medically reviewed by Drugs.com. Last updated on Aug 23, 2021.

Patients should be counseled that this product does not protect against HIV infection (AIDS) and other sexually transmitted diseases.

Rx only

Kimidess Description

Kimidess® provides an oral contraceptive regimen of 21 white round tablets each containing 0.15 mg desogestrel (13-ethyl-11-methylene-18,19-dinor-17 alpha-pregn- 4-en-20-yn-17-ol), 0.02 mg ethinyl estradiol (19-nor-17 alpha-pregna-1,3,5 (10)-trien-20-yne-3,17-diol), and inactive ingredients which include colloidal silicon dioxide, hypromellose, lactose monohydrate, povidone, polyethylene glycol, pregelatinized starch, stearic acid, and vitamin E, followed by 2 light-green tablets with the following inactive ingredients: FD&C Blue No. 2 aluminum lake, hypromellose, iron oxide yellow, lactose monohydrate, magnesium stearate, polyethylene glycol, and pregelatinized starch. The regimen also contains 5 yellow tablets containing 0.01 mg ethinyl estradiol (19-nor-17 alpha-pregna-1,3,5 (10)-trien-20-yne-3,17-diol) and inactive ingredients which include D&C yellow #10 HT aluminum lake, lactose monohydrate, hypromellose, magnesium stearate, polyethylene glycol and pregelatinized starch. The molecular weights for desogestrel and ethinyl estradiol are 310.48 and 296.40 respectively. The structural formulas are as follows:

USP dissolution test is pending.

Kimidess - Clinical Pharmacology

Combination oral contraceptives act by suppression of gonadotropins. Although the primary mechanism of this action is inhibition of ovulation, other alterations include changes in the cervical mucus (which increase the difficulty of sperm entry into the uterus) and the endometrium (which r...