Korlym
Generic name:mifepristone [ MIF-e-PRIS-tone ]
Drug classes:Progesterone receptor modulators, Uterotonic agents
What is mifepristone?
Korlym blocks the actions of a hormone called cortisol, which can reduce certain side effects caused by excess cortisol in the body.
Korlym is used to treat high blood sugar (hyperglycemia) in adults with Cushing's syndrome who also have type 2 diabetes mellitus or glucose intolerance.
Korlym should not be used to treat type 2 diabetes that is not related to Cushing's syndrome.
Mifeprex is another brand of mifepristone that is not covered in this medication guide.
Warnings
You should not take Korlym if you are a woman who still has her uterus and you have unexplained vaginal bleeding, endometrial hyperplasia, or a certain type of uterine cancer.
Do not use Korlym if you are pregnant. It could harm the unborn baby or cause a miscarriage. Use effective birth control to prevent pregnancy while you are using Korlym and for at least 1 month after your last dose.
You will need to have a negative pregnancy test before you start taking Korlym, or if you restart the medication after not taking it for longer than 2 weeks.
Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.
Before you take this medicine, tell your doctor if you have liver or kidney disease, heart disease, heart failure, coronary artery disease, high blood pressure, endometriosis, a problem with your thyroid or adrenal glands, or an autoimmune disorder.
Before taking this medicine
You should not take Korlym if you are allergic to mifepristone.
You should not take Korlym if you are a woman who still has her uterus and you have:
endometrial hyperplasia (changes in the cells lining your uterus);
endometrial cancer (cancer of the cells lining your uterus); or
unusual or unexplained vaginal bleeding.
Many drugs can interact and cause dangerous effects. Some drugs should not be used together with Korlym. Your doctor may change your treatment plan if you also use:
