Generic name:selumetinib [ SEL-ue-MET-i-nib ]
Drug class:Multikinase inhibitors
What is Koselugo?
Koselugo inhibits the actions of an enzyme which is often activated in different types of cancers.
Koselugo is a prescription medicine used to treat neurofibromatosis (a genetic disorder that causes tumors to develop on the nerves) in children at least 2 years old.
Neurofibromatosis may cause tumors in the brain or spinal cord, learning disabilities, tumors on or under the skin, or bone deformities. Plexiform neurofibromas are large tumors that grow from nerves anywhere in the body and may become cancerous later in life.
Koselugo is for children with plexiform neurofibromas that cannot be surgically removed.
Warnings
Tell your healthcare provider if you are taking aspirin, blood thinners, or other medicines to treat blood clots. Koselugo contains vitamin E which may increase your risk of bleeding.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
Koselugo should not be given to a child younger than 2 years old.
Tell your doctor if your child has ever had:
heart problems;
vision problems; or
liver problems.
A girl who has entered puberty may need to have a negative pregnancy test before starting this treatment.
Selumetinib can harm an unborn baby if the mother or father is using this medicine.
Girls who are able to get pregnant should use effective birth control to prevent pregnancy while taking Koselugo.
Boys with female sex partn...
