Kynamro

Generic name:mipomersen [ MYE-poe-mer-sen ]
Drug class:Miscellaneous antihyperlipidemic agents

Medically reviewed by Drugs.com. Last updated on Jun 28, 2021.

What is Kynamro?

Kynamro is a cholesterol-lowering medication. It reduces blood levels of "bad" cholesterol, such as low-density lipoprotein (LDL), apolipoprotein-B (apo-B), or non-high-density lipoprotein (non-HDL).

Kynamro is used together with a low-fat diet and other treatments to lower total cholesterol in people with homozygous familial hypercholesterolemia (an inherited type of high cholesterol). Kynamro is not for use in people with heterozygous familial hypercholesterolemia

It is not known whether Kynamro will lower your risk of heart disease.

Warnings

Kynamro is available only from a certified pharmacy.

You should not use Kynamro if you have active liver disease or abnormal liver function tests. Tell your doctor right away if you have liver symptoms, such as vomiting, fever, stomach pain, itching, tiredness, dark urine, or jaundice (yellowing of the skin or eyes).

Kynamro can cause your liver enzymes to get too high. Your blood will need to be tested often. Your treatments may be stopped based on the results of these tests.

Before using Kynamro

You should not use Kynamro if you are allergic to mipomersen, or if you have:

• active liver disease; or

• abnormal liver function tests.

To make sure this medicine is safe for you, tell your doctor if you have:

• cirrhosis or other liver disease;

• kidney disease (or if you are on dialysis); or

• if you drink alcohol.

Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using Kynamro.

Using Kynamro during pregnancy could harm the unborn baby. Tell your doctor if you are pregnant or if you become pregnant while using this medicine. Use effective birth control during treatment.

It is not known whether mipomersen passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

How is Kynamro given?

Take Kynamro exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Kynamro is injected under the skin. You may be shown how to use injections at home. Do not self inject this medicine if you do not understand how to give the injection and properly dispose of used needles and syringes.

Kynamro is usually given once per week. Use this medicine on the same day each week, at the same time of day.

Use a different place on your stomach, thigh, or upper arm each time you give the injection. Your care provider will show you the best places on your body to inject the medication. Do not inject into the same place two times in a row.

Kynamro is only part of a treatment program that may also include a special diet and other medications. F...