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LarkaDrin Capsules
  • Professionals
  • FDA PI

LarkaDrin Capsules

Generic name:acetaminophen, dichloralphenazone, and isometheptene mucate
Dosage form: capsule
Drug class:Antimigraine agents

Medically reviewed by Drugs.com. Last updated on Jun 21, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

BOXED WARNING

Hepatotoxicity:

LarkaDrin Capsules contain acetaminophen, dichloralphenazone, and isometheptene mucate. Acetaminophen has been associated with cases of acute liver failure at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4,000 milligrams per day, and often in combination with other acetaminophen-containing products.

LarkaDrin Capsules Description

Each LarkaDrin gelatin capsule contains:

Acetaminophen, USP ..... 325 mg

Dichloralphenazone, USP ..... 100 mg

Isometheptene Mucate, USP ..... 65 mg

Acetaminophen, a non-salicylate, occurs as a white, odorless, crystalline powder, possessing a slightly bitter taste. Acetaminophen is Acetamide, N-(4-hydroxyphenyl)-. It has the following structural formula:

Figure 1: Acetaminophen

C8H9NO2 M.W. 151.16

Dichloralphenazone is a white, microcrystalline powder, with slight odor and tastes saline at first, becoming acrid. It is a mild sedative. Its chemical name is: 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one, compound with 2,2,2-trichloro-1,1-ethanediol (1:2). Dichloralphenazone has the following structural formula:

Figure 2: Dichloralphenazone

C15H18Cl6N2