Latrix
Generic name:urea
Dosage form: topical suspension
Drug class:Topical emollients
Medically reviewed by Drugs.com. Last updated on Sep 21, 2021.
Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.
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(50% Urea) In a lactic acid & salicylic acid vehicle
For external use only.
Not for ophthalmic use.
The Latrix brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Latrix Description
Each gram of Latrix™ Topical Suspension contains: ACTIVE: 50% Urea in a topical suspension base of INACTIVES: consisting of Caprylic/Capric Triglyceride, Carbomer, Cetyl Alcohol, Edetate Disodium, Glycerin, Hydroxyethylcellulose, Lactic Acid, Linoleic Acid, PEG-6, Polysorbate 60, Propylene Glycol, Purified Water, Salicylic Acid, Sorbitan Stearate, Titanium Dioxide, Trolamine, Vitamin E and Xanthan Gum.
Urea is a diamide of carbonic acid with the following chemical structure:
Latrix - Clinical Pharmacology
Urea gently dissolves the intercellular matrix, which results in loosening the homy layer of skin and shedding scaly skin at regular intervals, thereby softening hyperkeratotic areas.
PHARMACOKINETICS
The mechanism of action of topically applied Urea is not yet known.
INDICATIONS AND USES
For debridement and promotion of normal healing of hyperkeratolic surface lesions, particularly where healing is retarded by local infection, necrotic tissues, fibrinour or purulent debris or eschar. Urea is useful for the treatment of hyperkeratotic conditions such as dry, rough skin, dermatitis, psoriasis, xerosis, ichthyosis, eczema, keratosis pilaris, keratosis Palmaris, keratoderma, corns and calluses.
Contraindications
Known hypersensitivity to any of the listed ingredients.
Warnings
For external use only. Avoid contact with eyes, l..
