Lefamulin (oral/injection)
Generic name: lefamulin (oral/injection) [ le-FAM-ue-lin ]
Brand name: Xenleta
Dosage forms: intravenous solution (150 mg/15 mL); oral tablet (600 mg)
Drug class:Miscellaneous antibiotics
What is lefamulin?
Lefamulin is used to treat certain types of pneumonia in adults.
Lefamulin may also be used for purposes not listed in this medication guide.
Warnings
Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.
Before taking this medicine
You should not use lefamulin if you are allergic to it.
Many drugs can interact and cause dangerous effects. Some drugs should not be used together with lefamulin. Your doctor may change your treatment plan if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.
Tell your doctor if you have ever had:
a heart rhythm disorder (especially if you take medication to treat it);
liver disease; or
kidney disease (or if you are on dialysis).
You may need to have a negative pregnancy test before starting this treatment.
Lefamulin may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using lefamulin and for at least 2 days after your last dose. Tell your doctor if you become pregnant.
You should not breastfeed within 2 days after using lefamulin. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.
How should I take lefamulin?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Lefamulin oral is taken by mouth.
Take lefamulin oral on an empty stomach, at least 1 hour before or 2 hours after a meal.
Take lefamulin oral with a full glass (6 to 8 ounces) of water. Swallow the tablet whole and do not crush, chew, or break it.
Lefamulin injection is given as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself.
Read and carefully follow any Instructions for Use provided with your medicine. A...
