#
Letairis
  • Treatments
  • Pulmonary Hypertension

Letairis

Generic name:ambrisentanAM-bri-SEN-tan ]
Drug class:Agents for pulmonary hypertension

Medically reviewed by Philip Thornton, DipPharm. Last updated on Sep 21, 2021.

What is Letairis?

Letairis prevents thickening of the blood vessels, especially those in the lungs and heart. Ambrisentan also lowers blood pressure in your lungs, helping your heart pump blood more efficiently.

Letairis is used to treat pulmonary arterial hypertension (PAH) in adults. It improves your ability to exercise and prevents your condition from getting worse.

Letairis is sometimes used with a medicine called tadalafil (Adcirca).

For women, Letairis is available only from a certified pharmacy under a special program. You must be registered in the program and sign agreements to use birth control and undergo pregnancy and blood testing.

Warnings

Letairis can harm an unborn baby or cause birth defects. Do not use if you are pregnant. You will need to take a pregnancy test before, during, and after treatment with ambrisentan.

If you are a woman of child-bearing potential, you will be required to use two forms of birth control to prevent pregnancy during your treatment, and for at least 1 month after your treatment ends.

You should not use Letairis if you have idiopathic pulmonary fibrosis.

Before taking this medicine

You should not use Letairis if you are allergic to ambrisentan, or if you have idiopathic pulmonary fibrosis (IPF).

Do not use Letairis if you are pregnant or think you might be pregnant. This medicine can cause serious birth defects. Tell your doctor right away if you miss a menstrual period or think you may have become pregnant.

You will need to have a negative pregn...