Letermovir (oral/injection)
Generic name: letermovir (oral/injection) [ le-TERM-oh-vir ]
Brand name: Prevymis
Dosage forms: intravenous solution (240 mg/12 mL; 480 mg/24 mL); oral tablet (240 mg; 480 mg)
Drug class:Miscellaneous antivirals
What is letermovir?
Letermovir is an antiviral medicine used to help prevent cytomegalovirus (CMV) infection after a stem cell (bone marrow) transplant from a donor. Letermovir is for use in adults who are seropositive for CMV. Seropositive means that the virus is in your blood even if you do not show any symptoms of infection.
A CMV-seropositive person is at risk for "reactivation" of the virus if the immune system becomes weak. While normally treatable, CMV infection can be serious in people undergoing a stem cell transplant.
Letermovir may also be used for purposes not listed in this medication guide.
Warnings
Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact with letermovir, and some drugs should not be used together.
Before taking this medicine
Some medicines can cause unwanted or dangerous effects when used with letermovir. Your doctor may need to change your treatment plan if you use any of the following drugs:
cholesterol medication--pitavastatin, simvastatin; or
ergot medicine--dihydroergotamine, ergotamine, ergonovine, methylergonovine.
Tell your doctor if you have ever had:
kidney disease;
diabetes; or
high cholesterol or triglycerides (a type of fat in the blood).
Tell your doctor if you are pregnant or breastfeeding.
How should I use letermovir?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Letermovir oral is taken by mouth.
Letermovir injection is given as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself.
You may take letermovir tablets with or without food.
Do not crush, chew, or break a letermovir tablet. Swallow it whole.
Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist ...
