Class: Quinolones
VA Class: AM900
Chemical Name: (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hydrate (2:1)
Molecular Formula: C18H20FN3O4•½H2O
CAS Number: 138199-71-0
Brands: Levaquin
Warning
- Serious Adverse Effects
Fluoroquinolones, including levofloxacin, have been associated with disabling and potentially irreversible serious adverse reactions (e.g., tendinitis and tendon rupture, peripheral neuropathy, CNS effects) that have occurred together. Discontinue immediately and avoid use of fluoroquinolones, including levofloxacin, in patients who have experienced any of these serious adverse reactions. (See Warnings under Cautions.)
Fluoroquinolones, including levofloxacin, may exacerbate muscle weakness in patients with myasthenia gravis. Avoid in patients with known history of myasthenia gravis.
Because of risk of serious adverse reactions, use levofloxacin for treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, or uncomplicated urinary tract infections (UTIs) only when no other treatment options available.
Introduction
Antibacterial; fluoroquinolone.
Uses for levoFLOXacin (Systemic)
Respiratory Tract Infections
Treatment of acute bacterial sinusitis caused by susceptible Streptococcus pneumoniae, Haemophilus influenzae, or Moraxella catarrhalis.
Treatment of acute bacterial exacerbations of chronic bronchitis caused by susceptible Staphylococcus aureus, S. pneumoniae, H. influenzae, H. parainfluenzae, or M. catarrhalis.
Use for treatment of acute bacterial sinusitis or acute bacterial exacerbations of chronic bronchitis only when no other treatment options availab..
