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Aminolevulinic acid
  • Treatments
  • Diagnosis and Investigation

Aminolevulinic acid

Generic name: aminolevulinic acid (oral) [ a-MEE-noe-LEV-ue-LIN-ik-AS-id ]
Brand name: Gleolan
Dosage form: oral powder for reconstitution (30 mg/mL)
Drug class:Malignancy photosensitizers

Medically reviewed by Drugs.com on Nov 10, 2021. Written by Cerner Multum.

What is aminolevulinic acid?

Aminolevulinic acid is given before surgery to remove a glioma (a type of brain or spinal cord tumor).

Taking aminolevulinic acid causes a certain substance to build up within your tumor tissue. This allows the tissue to be seen more clearly through a special light scope that is used during surgery to remove the tumor.

Aminolevulinic acid may also be used for purposes not listed in this medication guide.

Warnings

For 24 hours before and after taking aminolevulinic acid, you will need to protect your skin from light, both sunlight and bright indoor light.

Before taking this medicine

You should not use aminolevulinic acid if you are allergic to it, or if you have:

  • porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).

Tell your doctor if you have ever had liver or kidney disease.

Tell your doctor if you are pregnant.

You should not breast-feed within 24 hours after taking aminolevulinic acid. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.

How is aminolevulinic acid given?

Aminolevulinic acid is usually given about 3 hours before surgery. A healthcare provider will prepare and give you aminolevulinic acid.

For 24 hours before and after taking aminolevulinic acid, you will need to protect your skin from bright light. Avoid exposure to both sunlight and bright indoor light. Wear protective clothing and a wide-brimmed hat when you are outdoors. If you feel stinging or burning of the treated skin, reduce your exposure to light.

What happens if I miss a dose?

Aminolevulinic acid is used as a single dose and does not have a daily dosing schedule.

What happens if I overdose?

Since aminolevulinic acid is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid after taking aminolevulinic acid?

Avoid exposure to sunlight or bright indoor light for 24 hours after taking aminolevulinic acid. Wear a hat and clothing that covers your skin.

Aminolevulinic acid side effects

Signs of an allergic reaction may include:hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Your caregivers will watch you...