Dosage form: rectal suppository
Drug class:Topical anesthetics
Medically reviewed by Drugs.com. Last updated on Jan 1, 2021.
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Lidocaine Suppository Description
Each suppository for rectal administration contains 50 mg lidocaine in a specially blended hydrogenated vegetable base. Lidocaine is a local anesthetic of the amide type, which is chemically designated as acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-, and has the following structural formula:
Lidocaine Suppository - Clinical Pharmacology
Mechanism of action
Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting loc...
