Linagliptin and metformin

Generic name: linagliptin and metformin [ LIN-a-GLIP-tin-and-met-FOR-min ]
Brand names: Jentadueto, Jentadueto XR
Dosage forms: oral tablet (2.5 mg-1000 mg; 2.5 mg-500 mg; 2.5 mg-850 mg); oral tablet, extended release (2.5 mg-1000 mg; 5 mg-1000 mg)
Drug class:Antidiabetic combinations

Medically reviewed by Drugs.com on Apr 5, 2022. Written by Cerner Multum.

What is linagliptin and metformin?

Linagliptin and metformin are oral diabetes medicines that help control blood sugar levels. Metformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines. Linagliptin works by regulating the levels of insulin your body produces after eating.

Linagliptin and metformin is a combination medicine used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. linagliptin and metformin is not for treating type 1 diabetes.

Linagliptin and metformin may also be used for purposes not listed in this medication guide.

Warnings

You should not use this medicine if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment).

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Get emergency medical help if you have unusual muscle pain, trouble breathing, irregular heartbeats, dizziness, vomiting, or if you feel cold, tired, or very weak.

Before taking this medicine

You should not use linagliptin and metformin if you are allergic to linagliptin (Tradjenta) or metformin, or if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment with insulin).

Tell your doctor if you have ever had:

• kidney disease;

• heart disease;

• liver disease;

• pancreatitis;

• gallstones;

• alcoholism; or

• high triglycerides (a type of fat in the blood).

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if ...