Medically reviewed by Drugs.com. Last updated on Feb 6, 2022.
Discontinue lisinopril/hydrochlorothiazide as soon as possible when pregnancy is detected, as drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus .
Commonly used brand name(s)
In the U.S.
- Prinzide
- Zestoretic
Available Dosage Forms:
- Tablet
Therapeutic Class: ACE Inhibitor/Thiazide Combination
Pharmacologic Class: Diuretic
Chemical Class: Thiazide
Uses for lisinopril and hydrochlorothiazide
Lisinopril and hydrochlorothiazide combination is used to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure can reduce the risk of strokes and heart attacks.
Lisinopril is an angiotensin converting enzyme (ACE) inhibitor. It works by blocking a substance in the body that causes blood vessels to tighten. As a result, lisinopril relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart.
Hydrochlorothiazide is a thiazide diuretic (water pill). It reduces the amount of water in the body by increasing the flow of urine which helps lower the blood pressure.
Lisinopril and hydrochlorothiazide is available only with your doctor's prescription.
Before using lisinopril and hydrochlorothiazide
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For lisinopril and hydrochlorothiazide, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to lisinopril and hydrochlorothiazide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label o..
