Generic name: lithium carbonate
Dosage form: Tablets
Drug class:Antimanic agents
Medically reviewed by Drugs.com. Last updated on May 23, 2022.
On This Page
Lithium toxicity is closely related to serum lithium levels, and can occur at doses close to therapeutic levels. Facilities for prompt and accurate serum lithium determinations should be available before initiating therapy.
Lithane Description
Lithium carbonate is a white, light, alkaline powder with molecular formula Li2CO3 and molecular weight 73.89. Lithium is an element of the alkali-metal group with atomic number 3, atomic weight 6.94, and an emission line at 671 nm on the flame photometer.
Inert ingredients are: Blue 1 Lake; dibasic calcium phosphate; magnesium stearate; polyethylene glycol; sodium lauryl sulfate; starch; Yellow 5 Lake.
ACTIONS
Preclinical studies have shown that lithium alters sodium transport in nerve and muscle cells and effects a shift toward intraneuronal metabolism of catecholamines, but the specific biochemical mechanism of lithium action in mania is unknown.
INDICATIONS
Lithium carbonate is indicated in the treatment of manic episodes of manic-depressive illness. Maintenance therapy prevents or diminishes the intensity of subsequent episodes in those manic-depressive patients with a history of mania.
