Locoid Lotion
Generic name:hydrocortisone butyrate
Dosage form: topical lotion
Drug class:Topical steroids
Medically reviewed by Drugs.com. Last updated on Mar 1, 2021.
On This Page
- Indications and Usage
- Dosage and Administration
- Dosage Forms and Strengths
- Contraindications
- Warnings and Precautions
- Adverse Reactions/Side Effects
- Use In Specific Populations
- Description
- Clinical Pharmacology
- Nonclinical Toxicology
- Clinical Studies
- How Supplied/Storage and Handling
- Patient Counseling Information
Indications and Usage for Locoid Lotion
LOCOID® Lotion is indicated for the topical treatment of mild to moderate atopic dermatitis in patients 3 months of age and older.
Locoid Lotion Dosage and Administration
Apply a thin layer to the affected skin areas two times daily and rub in gently. Do not apply Locoid Lotion in the diaper area unless directed by a physician.
Discontinue therapy when control is achieved. If no improvement is seen within 2 weeks, reassessment of the diagnosis may be necessary. Before prescribing for more than 2 weeks, any additional benefits of extending treatment to 4 weeks should be weighed against the risk of HPA axis suppression and local adverse events. The safety and efficacy of Locoid Lotion has not been established beyond 4 weeks of use [see Warnings and Precautions (5.1)].
Do not use Locoid Lotion with occlusive dressings unless directed by a physician. Avoid use in the diaper area, as diapers or plastic pants may constitute occlusive dressings.
Locoid Lotion is not for oral, ophthalmic, or intravaginal use.
Dosage Forms and Strengths
Lotion, 0.1%. Each gram of Locoid Lotion contains 1 mg of hydrocortisone butyrate in a white to off-white lotion base. Locoid Lotion is supplied in bottles of 2 fl. oz. and 4 fl. oz.
Contraindications
None.
Warnings and Precautions
Hypothalamic-Pituitary-Adrenal (HPA) Axis Suppression
Systemic effects of topical corticosteroids may include reversible HPA axis suppression, manifestations of Cushing’s syndrome, hyperglycemia, and glucosuria.
Studies conduc...