Locoid Ointment

Generic name: hydrocortisone butyrate
Dosage form: ointment
Drug class:Topical steroids

Medically reviewed by Drugs.com. Last updated on Oct 22, 2021.

For topical use

Locoid Ointment Description

Locoid® (hydrocortisone butyrate) Ointment, 0.1% contains the topical corticosteroid, hydrocortisone butyrate, a non-fluorinated hydrocortisone ester. It has the chemical name: 11β, 17, 21-Trihydroxypregn-4-ene-3,20-dione 17-butyrate; the molecular formula: C25H36O6; the molecular weight: 432.54; and the CAS registry number: 13609-67-1.

Its structural formula is:

Each gram of Locoid® Ointment contains 1 mg of hydrocortisone butyrate in a base consisting of mineral oil and polyethylene.

Locoid Ointment - Clinical Pharmacology

Topical corticosteroids share anti-inflammatory, anti-pruritic and vasoconstrictive actions. The mechanism of anti-inflammatory activity of the topical corticosteroids is unclear. Various laboratory methods, including vasoconstrictor assays, are used to compare...