Amisulpride (Intravenous)

Medically reviewed by Drugs.com. Last updated on Mar 7, 2022.

Commonly used brand name(s)

In the U.S.

• Barhemsys

Available Dosage Forms:

• Solution

Therapeutic Class: Antiemetic

Pharmacologic Class: Dopamine Antagonist

Uses for amisulpride

Amisulpride injection is used alone or with other medicines to prevent and treat nausea and vomiting that may occur after surgery. Amisulpride works in the stomach to block the signals to the brain that cause nausea and vomiting.

Amisulpride is to be given only by or under the immediate supervision of your doctor.

Before using amisulpride

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For amisulpride, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to amisulpride or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects amisulpride injection for the prevention and treatment of nausea and vomiting after surgery in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of amisulpride injection in the elderly. However, elderly patients are more likely to have kidney problems, which may require caution and an adjustment in the dose for patients receiving amisulpride.

Breastfeeding

Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using amisulpride.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving amisulpride, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using amisulpride with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Bepridil
• Cisapride
• Dronedarone
• Mesoridazine
• Pimozide
• Piperaquine
• Saquinavir
• Sparfloxacin
• Terfenadine
• Thioridazine
• Ziprasidone

Using amisulpride with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Alfuzosin
• Amiodarone
• Amitriptyline
• Anagrelide
• Apomorphine
• Aripiprazole
• Aripiprazole Lauroxil
• ...