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Amitiza
  • Treatments
  • Irritable Bowel Syndrome

Amitiza

Generic name:lubiprostoneloo-bee-PROS-tone ]
Drug class:Chloride channel activators

Medically reviewed by Sanjai Sinha, MD. Last updated on Dec 13, 2021.

What is Amitiza?

Amitiza increases the secretion of fluid in your intestines to help make it easier to pass stools (bowel movements).

Amitiza is used to treat chronic chronic constipation, or constipation caused by opioid (narcotic) pain medicine.

Amitiza may also be used to treat irritable bowel syndrome in women with constipation as the main symptom.

Amitiza is only for use in adults.

Warnings

You should not use Amitiza if you have a blockage in your digestive tract, or if you have severe diarrhea.

Stop taking Amitiza and call your doctor if you feel light-headed every time you take this medicine or if you have severe diarrhea.

A nursing baby could develop diarrhea if the mother takes Amitiza while breast-feeding. Tell your doctor if you are breast-feeding a baby, and talk with your doctor if the baby develops diarrhea.

You may have tightness in your chest or feel short of breath within 1 hour of taking this medicine. This side effect should go away within 3 hours, but it may occur again when you take your next dose. Talk with your doctor if this side effect becomes bothersome.

Call your doctor at once if you have severe or ongoing nausea or diarrhea.

Before taking this medicine

You should not use Amitiza if you have a blockage in your digestive tract, or if you have severe diarrhea.

Tell your doctor if you have ever had liver disease.

Tell your doctor if you are pregnant or breastfeeding.

If you are breastfeeding, tell your doctor if you notice diarrhea in the nursing baby.

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