Medically reviewed by Drugs.com. Last updated on Apr 16, 2022.
Drugs that act directly on the renin-angiotensin system can cause injury or death to the developing fetus. Stop therapy as soon as possible when pregnancy is detected .
Commonly used brand name(s)
In the U.S.
- Hyzaar
Available Dosage Forms:
- Tablet
Therapeutic Class: Angiotensin II Receptor Antagonist/Thiazide Combination
Pharmacologic Class: Losartan
Chemical Class: Thiazide
Uses for losartan and hydrochlorothiazide
Losartan and hydrochlorothiazide combination is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure may reduce the risk of strokes and heart attacks.
Losartan and hydrochlorothiazide combination is also used to reduce the risk of stroke in patients with high blood pressure and enlargement of the heart.
Losartan is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes the blood vessels to tighten. Losartan relaxes the blood vessels and lowers the blood pressure. A lower blood pressure will increase the supply of blood and oxygen to the heart.
Hydrochlorothiazide is a thiazide diuretic (water pill) . It reduces the amount of water in the body by increasing the flow of urine, which helps lower the blood pressure.
Losartan and hydrochlorothiazide is available only with your doctor's prescription.
Before using losartan and hydrochlorothiazide
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For losartan and hydrochlorothiazide, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to losartan and hydrochlorothiazide or any other medicines. Also tell your health..
