Loteprednol Eye Gel

Generic name: loteprednol etabonate
Dosage form: ophthalmic gel
Drug class:Ophthalmic steroids

Medically reviewed by Drugs.com. Last updated on Jan 1, 2022.

Indications and Usage for Loteprednol Eye Gel

Loteprednol etabonate ophthalmic gel is a corticosteroid indicated for the treatment of post-operative inflammation and pain following ocular surgery.

Loteprednol Eye Gel Dosage and Administration

Invert closed bottle and shake once to fill tip before instilling drops.

Apply one to two drops of loteprednol etabonate ophthalmic gel into the conjunctival sac of the affected eye four times daily beginning the day after surgery and continuing throughout the first 2 weeks of the post-operative period.

Dosage Forms and Strengths

Loteprednol etabonate ophthalmic gel is a sterile preserved ophthalmic gel 0.5% containing 5 mg of loteprednol etabonate per gram of gel.

Contraindications

Loteprednol etabonate ophthalmic gel is contraindicated in most viral diseases of the cornea and conjunctiva including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella, in mycobacterial infection of the eye and fungal diseases of ocular structures.

Warnings and Precautions

Intraocular Pressure (IOP) Increase

Prolonged use of corticosteroids, including loteprednol etabonate ophthalmic gel, may result in glaucoma with damage to the optic nerve, defects in visual acuity and fields of vision. Steroids should be used with caution in the presence of glaucoma. If this product is used for 10 days or longer, intraocular pressure should be monitored.

Cataracts

Use of corticosteroids may result in posterior subcapsular cataract formation.

Delayed Healing

The use of steroids after cataract surgery may delay healing and increase the incidence of bleb formation. In those diseases causing thinning of the cornea or sclera, perforations have been known to occur with the use of topical steroids. The initial prescription and renewal of the medication order shou...