Generic name:amlodipine and benazepril [ am-LOE-di-peen-and-ben-AY-ze-pril ]
Drug class:ACE inhibitors with calcium channel blocking agents
What is Lotrel?
Lotrel contains a combination of amlodipine and benazepril. Amlodipine is a calcium channel blocker. Amlodipine relaxes (widens) blood vessels and improves blood flow.
Benazepril is an ACE inhibitor. ACE stands for angiotensin converting enzyme. Benazepril also widens blood vessels and also prevents the body from retaining water.
Lotrel is used to treat high blood pressure (hypertension).
Lotrel may also be used for purposes not listed in this medication guide.
Warnings
Do not use Lotrel if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away.
You should not use this medicine if you have ever had angioedema. Do not take this medicine within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).
If you have diabetes, do not use Lotrel together with any medication that contains aliskiren (a blood pressure medicine).
Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking Lotrel, which can lead to severely low blood pressure or a serious electrolyte imbalance.
Before taking this medicine
You should not use Lotrel if you are allergic to amlodipine or benazepril, or if:
you have had angioedema...